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A 15-year-old girl presents with painful oral ulcers that have been present for weeks, followed by the emergence of large, flaccid bullae on her trunk and groin. The Nikolsky sign is positive. A biopsy of perilesional skin with direct immunofluorescence shows an intercellular “chicken wire” pattern of IgG deposition. The circulating autoantibodies in this condition target which specific protein?

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