A 12-year-old on long-term phenytoin for seizures develops fever, rash, facial edema, lymphadenopathy, eosinophilia, and hepatitis 6 weeks after therapy initiation. What is the most likely diagnosis?
A 7-year-old with a history of atopic dermatitis presents for evaluation due to visual impairment and corneal scarring. His examination reveals bilateral periocular eczema, conjunctival redness, and mucoid discharge. Which ocular diagnosis should be considered?
A 9-year-old has extensive generalized urticaria, angioedema, fever, and arthralgias 10 days after antithymocyte globulin for kidney transplant. Labs show low C3 and C4, and thrombocytopenia. What is the likely underlying mechanism?
A 3-year-old is noted to have grouped, intensely pruritic papules on exposed legs, lasting > 1 week after playing outdoors. Which is the likeliest diagnosis?
A 16-year-old girl develops pruritic, burning wheals after exercise, hot showers, and stress, resolving within 1 hour. What type of urticaria is this?
A 7-year-old boy with a family history of asthma develops intermittent sneezing, itchy nose, and watery rhinorrhea mainly during spring. He often performs an upward rubbing of his nose. Which physical sign supports allergic rhinitis?
A 7-year-old boy experiences itchy, red, raised wheals 10 minutes after direct contact with animal saliva at a petting zoo. Which finding would confirm the diagnosis of contact urticaria?
A 12-year-old presents with periorbital edema and urticaria with arthritis and sensorineural hearing loss. Labs reveal elevated erythrocyte sedimentation rate and amyloidosis on renal biopsy. Which diagnosis fits best?
A 9-year-old with severe eczema is noted to have persistent pallor with frequent flares and a family history of asthma. Which additional cutaneous finding is characteristic of atopic dermatitis?
A 9-year-old presents with eyelid swelling, periorbital urticaria, and pruritus after exposure to dust mites but no pain or mucopurulent discharge. What topical medication is effective for symptom relief?
