A 16-year-old female presents with a week of profound fatigue, fever, and a severe exudative pharyngitis. Examination reveals posterior cervical lymphadenopathy and splenomegaly. A monospot test is positive. Her parents ask how long she will be contagious. What is the typical duration of Epstein-Barr virus shedding in oral secretions after an acute infection?
A 12-year-old girl who recently immigrated from sub-Saharan Africa presents for a well-child check. She complains of intermittent dysuria and has noticed blood in her urine. Infection with Schistosoma haematobium is suspected. In addition to potential renal failure and bladder cancer, what is a significant long-term complication for adolescent females with this specific infection?
An 16-year-old male is diagnosed with an uncomplicated urogenital Neisseria gonorrhoeae infection. His medical history is significant for a severe, anaphylactic reaction to ceftriaxone in the past. Which of the following is the most appropriate alternative treatment regimen for this patient?
A 10-year-old boy presents with a 10-day history of an abrupt-onset high fever, severe headache, and a nonproductive cough. His family recently purchased a cockatiel from a pet store, and the bird has had ruffled feathers and watery green droppings. Chest radiography shows a lobar infiltrate. What is the recommended treatment for this child’s most likely infection?
A renal transplant recipient (CMV D+/R-) is being managed post-transplant. The transplant team is monitoring for signs of cytomegalovirus infection. Which clinical presentation is best described as “CMV syndrome” in a solid organ transplant recipient?
A 14-year-old boy of Northern European descent presents with fatigue and pallor. His diet includes frequent consumption of raw salmon. Laboratory workup reveals megaloblastic anemia and a low vitamin B12 level. Stool microscopy shows operculated eggs. Which tapeworm is the most likely cause of his symptoms?
An adolescent male who is sexually active presents with a single, painful genital ulcer that has a ragged, undermined edge. He also has tender, unilateral inguinal lymphadenopathy. Tests for syphilis and herpes simplex virus are negative. Which single-dose oral therapy is a recommended first-line treatment for this condition?
A term infant is born to a 22-year-old mother who was diagnosed with primary syphilis during the 37th week of pregnancy and received a single dose of intramuscular benzathine penicillin G. Her RPR titer at diagnosis was 1:64, and at delivery two weeks later, it is 1:32. The infant is asymptomatic with a normal physical exam, and the infant’s RPR is 1:16. According to the evaluation algorithm, this infant’s situation is best categorized as?
An adolescent male with HIV-associated Kaposi sarcoma is started on combined antiretroviral therapy (ART). His skin lesions are mild and limited to the lower extremities. What is the most appropriate initial management for his Kaposi sarcoma?
A newborn infant is born to a mother who recently immigrated from a rural area in Bolivia. The infant has hepatosplenomegaly, anemia, and jaundice. Congenital Chagas disease is suspected. Which diagnostic test is most appropriate to confirm active infection in this neonate, given the presence of maternal antibodies?
