A newborn presents with recurrent infections, chronic diarrhea and failure to gain weight. What test helps in the rapid identification and treatment of infants with Severe Combined Immunodeficiency?
A 11-year-old presents with significant adenoid hypertrophy. Which deficiency leads to enlarged tonsils and lymph nodes within this age group?
A child experiences an episode of upper airways swelling due to glottis edema, which of the following does that correlate to?
A 7-year-old with hypogammaglobulinemia, neutropenia, and recurrent sinopulmonary infections is diagnosed with WHIM syndrome. Which therapy specifically targets the CXCR4 defect?
A 3-year-old with isolated sepsis caused by Streptococcus pneumoniae lacks a spleen on abdominal ultrasound. What peripheral blood finding supports the diagnosis?
A 14-month-old with SCID is undergoing workup for hematopoietic stem cell transplantation (HSCT). Which best minimizes the risk of early fatal infection while awaiting transplant?
A 10-year-old is undergoing HSCT for sickle cell disease with an available HLA-matched sibling. What is the expected probability of cure with this donor?
