A 10-year-old girl is evaluated for knee instability. Examination reveals that her thumbnails are hypoplastic with triangular lunulae, and her patellae are absent on palpation. Radiographs confirm absent patellae and show bony spines arising from the posterior aspect of her iliac bones. What is the most likely diagnosis?
A 7-year-old girl is diagnosed with pediculosis capitis. Her parents report having used an over-the-counter pyrethrin shampoo twice without success, and active lice are still seen on her scalp. Which of the following is an FDA-approved prescription therapy for this child?
A 12-year-old girl with a family history of a skin disorder presents with small, firm, warty papules on her chest and back that have coalesced into greasy, malodorous plaques. The eruption worsens with sweating in the summer. Nail dystrophy with longitudinal red and white banding is also noted. This condition is caused by a pathogenic variant in the gene encoding which cellular pump?
A 9-month-old infant with chronic, dry, thickened, scaly atopic dermatitis on his extensor surfaces is brought for a follow-up. The parents have tried creams with some success but find they have to reapply frequently. To maximize hydration and provide an occlusive barrier, which topical formulation is most preferable for this presentation?
A 2-week-old infant is brought in for a well-child check. The mother is concerned about “white dots” on the baby’s nose. On examination, you note numerous minute, yellow-white papules on the nose and forehead. You reassure the mother that these represent a benign, transient condition that will resolve in a few weeks. What is the most likely diagnosis?
A 16-year-old female is being treated for moderate inflammatory acne with a combination of a topical retinoid and benzoyl peroxide. She has not had an adequate response after 3 months. Which of the following would be the most appropriate next step in her management?
A 10-year-old boy presents with an abrupt eruption of numerous 2-3 mm papules with vesiculopustular centers that evolve to have dark, adherent, necrotic crusts. The lesions are diffusely distributed on his trunk and extremities. If medical treatment is required, which of the following is the most appropriate first-line agent?
A 4-year-old boy is brought for evaluation of recurrent fevers, especially in warm weather. His parents note he has very dry skin and sparse, fine hair. Examination reveals frontal bossing, a flattened nasal bridge, and widely spaced, conical teeth. A scalp biopsy would most likely reveal an absence of which structure?
A 2-month-old infant presents with a large, segmental hemangioma covering the right forehead and temporal area. The infant has been feeding well and is meeting developmental milestones. In addition to potential vision impairment, the presence of this hemangioma should prompt evaluation for which associated syndrome?
A 17-year-old sexually active male presents with multiple moist, fleshy, papillomatous lesions on his perianal mucosa. A diagnosis of condylomata acuminata is made. Which of the following is an appropriate first-line office-based treatment for these specific lesions?
