A 15-year-old female with obesity and a history of smoking presents with recurrent painful nodules and abscesses in her axillae and groin, leading to sinus tract formation and scarring. This condition, hidradenitis suppurativa, is part of a follicular occlusion tetrad that also includes acne conglobata, dissecting cellulitis of the scalp, and which other condition?
An 8-month-old infant presents with a nonpruritic, greasy, scaly, erythematous dermatitis on the scalp. Similar changes are noted in the retroauricular areas and the diaper area. What is the most appropriate initial management for the scalp lesions?
A 3-week-old infant is evaluated for intensely pruritic vesiculopustules that are most prominent on the palms and soles. The lesions have appeared in crops over the past week, with each outbreak lasting about 7-14 days followed by a brief remission. A Wright-stained smear of the intralesional contents shows abundant neutrophils. What is the most likely diagnosis?
A neonate is born encased in a thick, taut, translucent membrane resembling oiled parchment, leading to significant ectropion and a flattened appearance of the ears and nose. This “collodion baby” phenotype is most commonly a precursor to which of the following inherited skin disorders?
A 4-year-old malnourished child from a remote village in Africa presents with a rapidly progressing, painful, gangrenous ulcer on his cheek after a recent measles infection. This severe condition, known as noma, is best characterized as which of the following?
A 14-year-old obese male is brought to the clinic for a well-child check. His mother is concerned about symmetric, hyperpigmented, velvety plaques on his posterior neck and in his axillae, stating the skin looks “dirty” but does not wash off. This skin finding is a common cutaneous manifestation of what underlying condition?
A 7-year-old boy is brought to the hospital with a 1-week history of fever, cough, and severe mucositis involving his oral, ocular, and urogenital mucosa. On examination, he has a sparse vesiculobullous rash on his trunk, involving less than 10% of his body surface area. A PCR test from a throat swab is positive for Mycoplasma pneumoniae. Which diagnosis best fits this clinical picture?
A newborn is noted to have a solitary, well-demarcated 2-cm ulcerated lesion on the vertex of the scalp, surrounded by a ring of coarse, dark hair. The remainder of the physical examination is normal. The mother had an uncomplicated pregnancy and delivery. What is the most important next step in management?
A 2-year-old presents with fever, skin tenderness, and a diffuse scarlatiniform erythema that rapidly progresses to form flaccid blisters. Gentle pressure on the skin causes the epidermis to separate. The pathogenic mechanism involves hematogenous spread of staphylococcal epidermolytic toxins that cleave which specific protein? `
A 3-week-old full-term infant, who required whole-body cooling for perinatal asphyxia, develops several firm, violaceous, sharply demarcated subcutaneous nodules on his back and buttocks. The lesions are otherwise asymptomatic. The infant should be monitored for the development of which potentially serious complication over the next several months?
