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System: Part XXIX: The Skin

A 15-year-old male with a history of mild nodular acne abruptly develops extensive, tender, ulcerative lesions on his trunk, accompanied by a fever of 38.9°C (102°F), arthralgias, and leukocytosis. Osteolytic bone lesions are noted on imaging of his clavicle. Which treatment regimen is most appropriate for his condition?

A 6-year-old child is brought to the clinic for evaluation of hair loss. You suspect tinea capitis caused by a Microsporum species. Which diagnostic tool would be most useful in the office to support this specific diagnosis by detecting fluorescence?

A 10-year-old girl with Down syndrome develops a round, smooth patch of complete hair loss on her scalp. The underlying skin appears normal, and a hair pull test at the periphery is negative. Nail examination reveals fine pitting. What is the most likely diagnosis?

A 1-year-old infant is brought in for evaluation of patches of depigmented skin and a white forelock, both present since birth. Examination reveals widely spaced eyes and different colored irises. What is the most likely diagnosis, and what is the most significant associated non-cutaneous comorbidity?

A 17-year-old presents with multiple basal cell carcinomas on his face and trunk. He also has a history of odontogenic keratocysts removed from his jaw, and imaging reveals calcification of the falx cerebri. Which of the following findings would be LEAST expected as part of this patient’s condition, Nevoid Basal Cell Carcinoma Syndrome?

A 4-year-old child who is fed a restricted diet consisting primarily of rice milk presents with diffuse, fine, reddish-brown scaling of the skin described as “enamel/flaky paint,” thin depigmented hair, edema of the extremities, a protuberant abdomen, and “moon facies.” These findings are classic for which nutritional disorder?

A 6-year-old child presents with several honey-colored crusted plaques on his face. A culture of a lesion grows group A β-hemolytic streptococci. Which of the following is a known potential complication of this specific infection?

A 12-year-old boy with a history of recurrent herpes labialis presents with an abrupt, symmetric eruption of targetoid papules on the extensor surfaces of his upper extremities. The lesions have an erythematous outer border, a pale inner ring, and a dusky purple center. Which human leukocyte antigen is associated with an increased risk for the recurrent form of this condition?

A 4-year-old child with atopic dermatitis presents with numerous discrete, pearly, skin-colored, dome-shaped papules with central umbilication on his trunk and axillae. Some lesions are surrounded by an eczematous dermatitis. What is the most likely diagnosis?

An 18-month-old child presents with a superficial, fluid-filled blister on the volar fat pad of her thumb. There was no preceding trauma. A Gram stain of the purulent fluid from the blister identifies gram-positive cocci. What is the most likely diagnosis?

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